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SPRO

Spero Therapeutics, Inc.
LAST CLOSE… Pharmaceutical Preparations SHARES +3.5% · 12M
80
SEVERE
RISK INDEX
RED FLAGS 72 SHARE PRINTING 4 YEARS-LONG PATTERN 4 = 80/100. WHY THIS NUMBER, PIECE BY PIECE.

THE READ 48 red-flag mentions across this year's filings, led by dilution and going concern doubt, and 151 since 2001, so this is a long-running pattern; share count roughly stable.

FLAGS DILUTION CASH WHAT CHANGED VERDICT INSIDERS OUTSIDE RECORDS
01

Red Flags

2025-08-30 → 2026-08-30

We read every document this company filed with the SEC this year and counted the classic danger phrases. Where wording can be misleading, we open the actual documents and separate real warnings from accounting boilerplate. Each hit links to the exact document.

Dilution (at the market offering) AT LEAST 13 REAL WARNINGS · 7 matching docS this year · 46 ALL TIME

An ATM lets the company print and sell new shares into the market any day it wants. Every print dilutes your slice.

EVIDENCE: [1] 8-K FILED 2026-08-28 · [2] S-3 FILED 2026-08-28 · [3] S-3 FILED 2026-08-28 · [4] 10-Q FILED 2025-11-13 · [5] 10-Q FILED 2026-05-13

Reverse stock split 0 REAL WARNINGS · 1 matching doc this year · 38 ALL TIME

A reverse split shrinks the share count to lift the price above $1. Repeat reverse splits are the classic death-spiral signature.

EVIDENCE: [1] 10-Q FILED 2026-08-12

Going concern doubt 32 REAL WARNINGS · 5 matching docS this year · 48 ALL TIME

Auditors flagged substantial doubt the company survives the next 12 months without new money.

EVIDENCE: [1] 10-Q FILED 2026-05-13 · [2] 10-Q FILED 2025-11-13 · [3] 10-Q FILED 2026-08-12 · [4] 10-K FILED 2026-03-26 · [5] 10-Q FILED 2026-08-12

Delisting / exchange risk 3 REAL WARNINGS · 2 matching docS this year · 19 ALL TIME

The exchange has threatened to kick the stock off. Delisting pressure usually ends in a reverse split or a fire-sale raise.

EVIDENCE: [1] S-3 FILED 2026-08-28 · [2] 10-Q FILED 2025-11-13

SOURCE: FULL-TEXT SEARCH OF THE COMPANY'S OFFICIAL SEC FILINGS. "REAL WARNINGS" = WE OPENED THE LINKED DOCUMENTS AND FILTERED PHRASES WRAPPED IN NEGATIONS, RESOLUTION LANGUAGE OR STANDARD CONTRACT TERMS. "AT LEAST" = MORE DOCUMENTS CARRY THE PHRASE THIS YEAR THAN WE COULD OPEN AND READ.

02

The Printing Press

How many shares exist, over time, exactly as the company reported in its own filings. In microcaps, a rising share count is how holders pay for everything: salaries, debts, and bad deals. Sudden collapses in the line are reverse splits, marked below.

14,369,182 shares · 2017-11-30 58,234,827 shares · 2026-08-07 LAST 12M: +3.5% AVG/YEAR SINCE 2017: +17.5%

SOURCE: THE COMPANY'S OWN REPORTED SHARE COUNTS ACROSS 36 FILINGS, STRAIGHT FROM SEC RECORDS

CHECKING OFFICIAL SPLIT RECORDS…

What this means for YOUR shares

Type how many shares you hold. The math is plain division on the company's own reported counts.

03

Cash Countdown

Cash in the bank against how fast the company burns it. When this hits zero, the next stop is usually a desperate raise at bad terms, and existing holders pay through dilution.

$50.77M
CASH ON HAND
latest reported quarter
-9.5%
CASH CHANGE QoQ
latest two reported quarters
2024·92024·122025·32025·62025·92025·122026·32026·6
CASH OVER TIME, LAST 8 REPORTED QUARTERS $76.29M → $50.77M TREND: -33.4%

RUNWAY = CASH ON HAND ÷ MONTHLY CASH BURN. SIMPLE ARITHMETIC ON THE COMPANY'S OWN REPORTED NUMBERS, NOT A PROJECTION.

04

What the Newest Filing Changed

The latest filings, translated into holder impact. Every number cites its form, date and SEC link.

Shares outstanding +0.6%

Shares outstanding rose 57.90M to 58.23M (+0.6%) between 10-Q 2026-05-01 and 10-Q 2026-08-07.

NOW: 58,234,827 as of 2026-08-07 (10-Q, filed 2026-08-12)

WAS: 57,901,493 as of 2026-05-01 (10-Q, filed 2026-05-13)

Cash and equivalents -9.5%

Cash and equivalents fell $56.13M to $50.77M (-$5.36M, -9.5%) between 10-Q 2026-03-31 and 10-Q 2026-06-30.

NOW: $50.77M as of 2026-06-30 (10-Q, filed 2026-08-12)

WAS: $56.13M as of 2026-03-31 (10-Q, filed 2026-05-13)

Total assets -10.6%

Total assets fell to $52.77M (from $59.02M, -10.6%) between 10-Q 2026-03-31 and 10-Q 2026-06-30.

NOW: $52.77M as of 2026-06-30 (10-Q, filed 2026-08-12)

WAS: $59.02M as of 2026-03-31 (10-Q, filed 2026-05-13)

Total liabilities +40.7%

Total liabilities rose to $8.56M (from $6.09M, +40.7%) between 10-Q 2026-03-31 and 10-Q 2026-06-30.

NOW: $8.56M as of 2026-06-30 (10-Q, filed 2026-08-12)

WAS: $6.09M as of 2026-03-31 (10-Q, filed 2026-05-13)

Revenue -100.0%

Revenue fell $258K to $0 (-100.0%) between the period ended 2026-03-31 and the period ended 2026-06-30 (10-Q).

NOW: $0 as of 2026-06-30 (10-Q, filed 2026-08-12)

WAS: $258K as of 2026-03-31 (10-Q, filed 2026-05-13)

Cash burn / runway

Operating cash flow was positive ($10.51M) over the period ended 2026-06-30; no cash deficit to burn.

NOW: $10.51M as of 2026-06-30 (10-Q, filed 2026-08-12)

!

Critical 8-K Ledger

OFFICIAL NOTICES · 24 MO

When something material happens, the company itself must announce it in an 8-K under the SEC's numbered item system. These are those announcements, newest first: bankruptcy papers, exchange delisting warnings, auditor changes, financials pulled back. Read straight from the SEC filing index, no interpretation layer.

2026-07-14 ITEM 2.03 · NEW DIRECT OBLIGATION FILING ↗
2026-06-25 ITEM 5.02 · OFFICER / DIRECTOR EXIT FILING ↗
2026-01-30 ITEM 5.02 · OFFICER / DIRECTOR EXIT FILING ↗
2025-06-18 ITEM 5.02 · OFFICER / DIRECTOR EXIT FILING ↗
2025-04-28 ITEM 5.02 · OFFICER / DIRECTOR EXIT FILING ↗
2025-02-28 ITEM 3.01 · DELISTING / EXCHANGE NOTICE FILING ↗
2025-01-10 ITEM 5.02 · OFFICER / DIRECTOR EXIT FILING ↗

SOURCE: THE ITEM NUMBERS THE COMPANY ITSELF PUT ON EACH 8-K IN THE SEC'S FILING INDEX. HOVER A STAMP FOR WHAT THAT ITEM MEANS FOR YOUR SHARES. OFFICIAL NOTICES INSIDE THE LAST 12 MONTHS ALSO FEED THE RISK INDEX ABOVE (CAPPED AT 15 POINTS).

2024·32024·62024·92025·32025·62025·92026·32026·6
QUARTERLY REVENUE, LAST 8 QUARTERS $9.27M → $0 TREND: -100.0%

EACH BAR IS ONE REPORTED QUARTER. GREEN = MOST RECENT QUARTER GREW VS THE ONE BEFORE.

!

Breaking Filing

8-K · 2026-08-28

An 8-K is the "something happened right now" filing. Here is what this one says, in the company's own words.

Item 1.01

On August 28, 2026, Spero Therapeutics, Inc., a Delaware corporation (the “Company”), entered into an Open Market Sale Agreement℠ (the “Sale Agreement”) with Jefferies LLC, as agent (“Jefferies”), pursuant to which the Company may offer and sell shares (the “Shares”) of its common stock, $0.001 par value per share (the “Common Stock”), from time to time through Jefferies (the “Offering”). The Company has filed a universal shelf Registration Statement on Form S-3 (“Registration Statement”) with the Securities and Exchange Commission (the “SEC”) for the offer and sale of up to a maximum aggregat...

Item 8.01

As previously disclosed, on March 11, 2021, the Company entered into a Controlled Equity Offering℠ Sales Agreement (the “Cantor Sales Agreement”) with Cantor Fitzgerald & Co., as agent (“Cantor”), pursuant to which the Company could offer and sell shares of Common Stock from time to time through Cantor (the “Cantor ATM Offering”). The Company filed a prospectus with the SEC on March 15, 2024 in connection with the Cantor ATM Offering (the “Cantor Prospectus”). The Cantor Prospectus was filed under a universal shelf Registration Statement on Form S-3 filed with the SEC on March 15, 2024, which...

READ THE ORIGINAL FILING

05

The Verdict

AVOID · HIGH CONFIDENCE

A rules-based reading of the cited filing facts: a range with reasons, never a prediction.

AVOID
SCREENING VERDICT
HIGH confidence
$1.13-$1.13
FAIR VALUE BRACKET
trailing revenue of $0.3415/share at 1.0-3.0x
$1.20
LAST CLOSE
non-realtime

HOW THE BRACKET IS BUILT: TRAILING REVENUE OF $0.3415/SHARE AT 1.0-3.0X · BOOK EQUITY OF $2.27/SHARE AS A SUPPORT LEVEL · CASH FLOOR: $0.8719/SHARE IN A WIND-DOWN.

BASIS FOR

+1

Share count is stable-ish (+0.6% change between the last two reported quarters).

+2

Fair-value range anchored to cited facts: $1.13 to $1.13 per share.

AGAINST

−1

The filings do not report usable cash and operating-burn figures, so runway could not be computed for this verdict.

−2

Revenue fell 100.0% period over period.

−3

Verified going-concern warnings in a recent filing: auditors or management flagged substantial doubt about continuing (document text checked, boilerplate excluded).

METHOD: DETERMINISTIC RULES OVER CITED SEC FILING FACTS: SHARE-COUNT CHANGE BETWEEN THE LAST TWO REPORTED QUARTERS (DILUTION), CASH-TO-BURN RUNWAY FROM THE MOST RECENT OPERATING CASH FLOW, PERIOD-OVER-PERIOD REVENUE GROWTH, AND A FAIR-VALUE RANGE ANCHORED TO CASH PER SHARE VS PRICE. THRESHOLDS ARE TUNABLE IN APP/VERDICT_ENGINE.PY. NOT A PREDICTION.

06

Insider Paper Trail

NET SELLING

Every time an officer, director or big owner trades shares, the law makes them file a Form 4 within two business days. We read the actual filings: who traded, what kind of trade, how big, at what price.

0
OPEN-MARKET BUYS
nobody is buying with their own cash
1
OPEN-MARKET SELLS
25,240 shares · ~$63K cashed out
16
GRANTS / AWARDS
696,986 new shares/options handed out: future dilution
DATEWHOACTION
2026-08-03 Zack Debra GRANT/AWARD 162,311
2026-08-03 Zack Debra GRANT/AWARD 324,675 OPTIONS/DERIVATIVE
2026-06-23 Deshpande Milind GRANT/AWARD 10,000
2026-06-23 Deshpande Milind GRANT/AWARD 20,000 OPTIONS/DERIVATIVE
2026-06-23 Tregoning Kathleen GRANT/AWARD 10,000
2026-06-23 Tregoning Kathleen GRANT/AWARD 20,000 OPTIONS/DERIVATIVE
2026-06-23 Smith Cynthia GRANT/AWARD 10,000
2026-06-23 Smith Cynthia GRANT/AWARD 20,000 OPTIONS/DERIVATIVE
2026-06-23 VINK PATRICK V.J.J. GRANT/AWARD 10,000
2026-06-23 VINK PATRICK V.J.J. GRANT/AWARD 20,000 OPTIONS/DERIVATIVE
2026-06-23 THOMAS FRANK E GRANT/AWARD 10,000
2026-06-23 THOMAS FRANK E GRANT/AWARD 20,000 OPTIONS/DERIVATIVE

PEOPLE WITH THE BEST INFORMATION ABOUT THIS COMPANY ARE SELLING MORE THAN THEY BUY. NOT PROOF OF ANYTHING: EXECUTIVES SELL FOR MANY REASONS. BUT AT MICROCAP SCALE, IT RARELY SMELLS GOOD. "10B5-1 PLAN" MEANS THE TRADE WAS SCHEDULED UNDER A PRE-SET TRADING PLAN, DISCLOSED IN THE FILING'S OWN FOOTNOTES: PRE-PLANNED SALES CARRY LESS SIGNAL THAN SPUR-OF-THE-MOMENT ONES. SOURCE: FORM 4 FILINGS, PARSED FROM THE SEC'S OWN XML, LAST 9 FILINGS.

07

Filing Timeline

The company's most recent SEC paperwork, newest first.

8-K 2026-08-28 0001193125-26-374788
S-3 2026-08-28 0001193125-26-374702
8-K 2026-08-12 0001193125-26-346855
10-Q 2026-08-12 0001193125-26-346795
4 2026-08-06 0001807743-26-000007
3 2026-08-06 0001807743-26-000005

SOURCE: THE COMPANY'S SEC FILING INDEX

08

Outside the Filings

Public records that most investors never check, cross-checked against what the company claims. This is where shells slip up.

dfinsolutions.com
WEB ADDRESS ON RECORD
registered 2018-05-03 · via MarkMonitor Inc.
8.3 YRS OLD
DOMAIN AGE
old and consistent with an operating company: a good sign
0
OFFICIAL OFFERING DOCS · 12M
no completed stock sales to the public in a year
1
SHELF REGISTRATIONS · 12M
paperwork filed to allow future share sales: future dilution waiting
0
BIG-OWNER TAKEOVER FILINGS · 12M
no outside investor has crossed the 5% disclosure line this year
PUBLIC FLOAT
shares actually tradable, vs held by insiders and big owners
SOLD SHORT
FINRA short interest: how many shares are bets against this company, and how many days of trading it would take to cover
CLEAR
US SANCTIONS SCREEN
company name checked against the official US sanctions list (19290 entries)
LEGAL IDENTITY (LEI)
every company that trades securities must carry a global legal identifier: status, parent chain and subsidiaries from the official registry
INSTITUTIONAL HOLDERS · 13F
quarterly institutional holdings filings scanned for this exact company name: which funds still report holding shares, from their own filings
SITE HISTORY
how long the company's website has been around, per the public web archive
CERT RECORD
public certificate logs date the company's web infrastructure: old and boring is good, brand-new is a tell
REGISTRANT HISTORY
old snapshots of public WHOIS pages: has the registered owner of this address changed hands
HOSTING + MAIL RECORDS
public DNS records: where the address is pointed and whether it can even receive mail

SOURCES: PUBLIC DOMAIN REGISTRATION RECORDS (FOUND IN THE COMPANY'S OWN FILING SIGNATURES) · THE COMPANY'S SEC FILING INDEX · OFFICIAL US SANCTIONS LIST · QUARTERLY 13F FILINGS VIA EDGAR FULL-TEXT SEARCH · LEGAL-IDENTITY, SITE-HISTORY, CERTIFICATE, REGISTRANT-HISTORY AND DNS SLOTS STREAM IN FROM FREE PUBLIC REGISTRIES WITHOUT BLOCKING THIS PAGE.

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09

Company Record

Legal nameSpero Therapeutics, Inc.
Fiscal year end1231
HQ675 MASSACHUSETTS AVENUE, 14TH FLOOR, CAMBRIDGE, MA
Last periodic report2026-08-12 (10-Q, 18d ago)
Shares outstanding58,234,827 as of 2026-08-07 (10-Q)

SOURCE: THE COMPANY'S SEC FILING INDEX

Next time SPRO files something scary, know within minutes.

One Telegram message per material filing: dilution, going concern, delisting, insider dumps. No account, no email. Every line cites its SEC source. Leave anytime with /unwatch.

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